| Area | EPUB3Specification | EPUB 2.0.1 Specification |
| Overview | EPUB3 Overview | (throughout) |
| Publication-level Specification & Package Docs | EPUB Publications 3.0 | Open Packaging Format 2.0.1 |
| Content-level Specification | EPUB Content Documents 3.0 | Open Publication Structure 2.0.1 |
| NCX Documents | EPUB Publications 3.0 | N/A (referenced as DAISY specification) |
| Media Overlays | EPUB Media Overlays 3.0 | N/A |
| Container packaging | Open Container Format 3.0 | Open Container Format 2.0.1 |
| Differences from previous version | EPUB3 Differences from EPUB 2.0.1 | (throughout) |
這是新舊規格內容的差異表，我覺得這真是很聰明的改變。從這裡可以看出一件很重要的事情：EPUB2跟EPUB3不相容。所以不用浪費力氣去作 RS 的整合了，直接開發新版閱讀軟體才是王道。
| EPUB3 Term | EPUB 2.0.1 Term |
| Content Document | OPS Content Document |
| User Agent (in EPUB Content Documents 3.0) | Reading System (in OPS 2.0.1) |
| OCF Processor (in OCF 3.0) | Reading System (in OCF 2.0.1) |
| EPUB Publication (in EPUB Publications 3.0) | OPS Publication (in OPF 2.0.1) |
| XHTML Content Documents | XHTML documents |
這是新舊規格名詞的差異表，要注意的是"Reading System"從此不再存在了，取而代之的是"User Agent"以及"OCF Processor"
